Interaction of Orally Administered 5-{3-(((2S)-1 ,4-Benzodioxan-2-ylmethyl)amino)propoxy}-1,3-benzodioxole (MKC-242) with 5-HT1A Receptors in Rat Brain.
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منابع مشابه
Effects of a benzodioxan derivative MKC-242 on the firing activity of the dorsal hippocampus CA1 pyramidal neurons in awake and urethane- anaesthetized rats: in vivo electrophysiological evidence for a 5-HT 1A agonistic property.
The aim of the present in vivo study was to determine whether a benzodioxan derivative MKC-242, (S)-5-[3-[(1,4-benzodioxan-2-ylmethyl)amino]propoxy]-1,3-benzodioxole hydrochloride, possesses an agonistic activity at postsynaptic serotonin (5-HT)1A receptors in the rat hippocampus when administered systemically. We examined the effects of acute administrations of MKC-242 on the firing activities...
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ژورنال
عنوان ژورنال: The Japanese Journal of Pharmacology
سال: 1997
ISSN: 0021-5198,1347-3506
DOI: 10.1254/jjp.74.69